Although sonodynamic therapy (SDT) is a promising non-invasive tumor treatment strategy due to its safety, tissue penetration depth and low cost, the hypoxic tumor microenvironment limits its therapeutic effects.Herein, we have designed and developed an oxygen-independent, ROS-amplifying chemo-sonodynamic antitumor therapy based on novel pH/GSH/ROS
Copy number variation through gene or chromosome amplification provides a route for rapid phenotypic variation and supports the long-term evolution of gene functions.Although the evolutionary importance of copy-number variation is known, little is understood about how genetic background influences its tolerance.Here, we measured fitness costs of ov
The effects of a baffle and chemical reaction (first-order) on liquid flow in an upright double-passage channel were studied using regular perturbation analysis.Each of the two streams has its pressure gradient, temperature and velocity, and the channel is partitioned into two channels by a thin baffle that is fully conductive and flat in shape.The
The composition of a plant virome may represent spatiotemporal patterns of plant virus abundance.Using next generation sequencing, we investigated the viromes of watermelon fruits grown in two adjacent open fields located in Eastern Israel: Kalia and Mitzpe-Shalem.The two viromes were comprised of distinct virus species and genera.Studying spatial
frog castanet The increasing penetration of wind power in the grid has driven the integration of wind farms with power systems that are series-compensated to enhance power transfer capability and dynamic stability.This may lead to sub-synchronous control interaction (SSCI) problems in series-compensated doubly-fed induction generator (DFIG)-based w